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De som är känsliga fileör de androgena biverkningarna av Trenbolone Enanthate kommer ofta att försöka bekämpa dem med en five-alfa-reduktashämmare. Detta är mycket vanligt och är också slöseri med tid. Sådana hämmare, varvid Finasteride är primär, används vanligen fileör att minska androgeniciteten hos en steroid som bringas vidare
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